If Lyme illness wasn’t scary sufficient, there’s one other harmful danger tick bites carry: the chance of creating alpha-gal syndrome, a probably life-threatening allergy to crimson meat.
As a registered dietitian, I get requested by an increasing number of shoppers about what you’ll be able to and can’t eat with a crimson meat allergy. That’s why I created this useful resource on the alpha-gal allergy eating regimen to assist. Learn on to study extra about what alpha-gal syndrome is, who’s in danger, and what to eat when you’ve got a crimson meat allergy.
This submit accommodates affiliate hyperlinks. As all the time, all opinions are my very own.
What’s alpha-gal allergy?
Alpha-gal syndrome (AGS), often known as alpha-gal allergy, is a critical and probably life-threatening allergic response to crimson meat and different merchandise produced from mammals. It was solely just lately found and linked with tick bites in 2009 and has been rising in prevalence ever since as tick populations swell and their ranges broaden.

In response to the Facilities for Illness Management and Prevention (CDC), the variety of folks identified with alpha-gal syndrome in the US has risen from 12 in 2009 to over 34,000 in 2019.
AGS is prompted by bites from sure sorts of ticks that carry alpha-gal of their saliva.
- The α-Gal syndrome is a fancy allergic illness characterised by the event of particular IgE antibodies towards the carbohydrate galactose-α-1,3-galactose (α-Gal), an oligosaccharide current in cells and tissues of non-primate mammals.
- AGS happens when the physique’s immune system produces antibodies to alpha-gal after being bitten by a tick that carries the molecule.
- The time delay between consuming meat merchandise and getting an allergic response could also be one purpose AGS was not understood at first. Researchers assume that is as a result of alpha-gal molecules taking longer than different allergens to be digested and enter the bloodstream.
What are the signs of AGS?

AGS reactions happen upon the ingestion of alpha-gal in meat merchandise and might embody hives or an itchy rash, nausea or vomiting, heartburn or indigestion, diarrhea, cough, shortness of breath, or issue respiratory.
AGS reactions could be totally different from individual to individual and might vary from gentle to extreme and even life-threatening. Anaphylaxis, a probably life-threatening response involving a number of organ techniques, may have pressing medical care.
What ticks trigger AGS?
Alpha-gal allergy is primarily related to the chunk of the lone star tick (Amblyomma americanum) in the US. Nonetheless, different tick species have additionally been related with the event of alpha-gal allergy in different international locations.

The lone star tick is primarily discovered in jap, southeastern, and central midwestern areas all through the US.
The precise mechanism by which tick bites set off the event of alpha-gal allergy is nonetheless being studied. It is very important notice that not everybody who’s bitten by ticks will develop alpha-gal allergy, and the chance components for creating the allergy are nonetheless not totally understood.
How is alpha-gal allergy identified?
Alpha-gal syndrome is comparatively new and never all the time simple to diagnose.
Diagnosing alpha-gal allergy includes a mix of affected person historical past, bodily examination, and particular medical assessments. Here’s a breakdown of the diagnostic course of:

- Affected person historical past:
- Your healthcare supplier will ask about your signs, together with any allergic reactions you will have skilled after consuming crimson meat or different merchandise containing alpha-gal.
- They might inquire about tick bites or publicity to areas the place ticks are prevalent.
- Bodily examination:
- Your healthcare supplier might conduct a bodily examination to evaluate any seen indicators of allergic reactions or different associated signs.
- Blood check:
- A blood check is a key diagnostic device for alpha-gal allergy.
- The blood check measures the degrees of particular antibodies referred to as IgE antibodies to alpha-gal in your bloodstream.
- Elevated ranges of IgE antibodies to alpha-gal can point out an allergic response to alpha-gal.
- Pores and skin check:
- In some instances, a pores and skin check could also be carried out.
- Throughout a pores and skin check, small quantities of drugs derived from crimson meat are pricked into the pores and skin.
- In case you are allergic to alpha-gal, chances are you’ll develop a raised bump or hive on the check website in your pores and skin.

It is very important notice that the analysis of alpha-gal allergy must be made by a healthcare skilled, akin to an allergist or immunologist.
In case you suspect you will have alpha-gal allergy, it’s endorsed to keep away from consuming crimson meat and different merchandise containing alpha-gal till you will have been correctly identified and suggested by a healthcare supplier.
What are you able to eat if you’re dwelling with an alpha-gal allergy?

When you’ve got been identified with AGS, you will have to keep away from all mammalian meat and organs, together with beef, pork, lamb, and venison.
For some folks with AGS, reactions to take advantage of and dairy merchandise, gelatin, and/or carrageenan can happen and can must be prevented.
In case you are dwelling with AGS, it is very important work along with your healthcare supplier and a registered dietitian to develop a meal plan that meets your dietary wants and consists of meals you take pleasure in whereas stopping the chance of an allergic response.
What meals do it is advisable to keep away from with AGS?

In case you are dwelling with alpha-gal allergy, it is very important keep away from all mammalian meat and organs, together with beef, bison, pork, lamb, mutton, venison, rabbit, and goat. This additionally consists of any meals that accommodates crimson meat extracts.
Some people with alpha-gal allergy should additionally keep away from dairy merchandise produced from cow’s, sheep’s or goat’s milk. Here’s a detailed checklist of meals and substances to keep away from with an alpha-gal allergy:

- – Beef
- – Bison
- – Pork
- – Lamb
- – Mutton
- – Venison
- – Rabbit
- – Goat
- – Any meals that accommodates crimson meat extracts
- – Dairy merchandise produced from cow’s, sheep’s or goat’s milk
- – Brown gravy made with beef broth
- – Gelatin produced from byproducts of meat and leather-based business
- – Sure vaccines
- – Gummy candies (until vegan)
- – Some ice cream and yogurt
- – Gelatin desserts
- – Marshmallows[
- – Altoids brand mints
- – Gelatin capsules (vitamins, supplements, and RX meds in gelatin capsules)
- – Medications that contain pre-gelatinized starch
- – Lard (some refried beans contain lard)
- – Magnesium stearate in pills
- – Tic-tacs (some have pork derivatives in them)
- – Lanolin (sheep)
- – Leather (shoes, couches, coats)
- – Pets/animal contact/inhalation can trigger cough
It is important to work with a registered dietitian to develop a meal plan that meets your nutritional needs and helps you manage your alpha-gal allergy.
All fruits, vegetables, grains, nuts, legumes, poultry, and seafood are appropriate for alpha-gal allergies.
Hidden ingredients to avoid with alpha-gal syndrome
When living with alpha-gal allergy, it is important to be aware of hidden ingredients that may contain alpha-gal or trigger an allergic reaction. Here are some common hidden ingredients to avoid with alpha-gal allergy:

- Sugary foods: Some sugar products, such as certain candies or sweets, may contain gelatin derived from mammalian sources.
- Gelatin: Gelatin is commonly derived from animal sources, including mammals. It is often used as a gelling agent in food products, such as desserts, marshmallows, gummy candies, and gelatin-based desserts.
- Whey & Casein: Whey and casein are proteins found in milk and dairy products. Some individuals with alpha-gal allergy may also react to dairy products made from cow’s, sheep’s, or goat’s milk. This includes milk, cheese, yogurt, butter, and other dairy-containing foods.
- Tallow & Lard: Tallow is a type of fat derived from animals, including mammals. Lard is specifically derived from pigs. These fats can be found in certain processed foods, such as baked goods, fried foods, and snacks.
- Vitamin D: Vitamin D supplements may contain gelatin derived from mammalian sources. It is important to check the ingredients or consult with a healthcare professional to ensure the supplement is free from mammalian-derived ingredients.
It is crucial to carefully read food labels and ingredient lists to identify any potential sources of alpha-gal or hidden ingredients derived from mammals. Additionally, working with a registered dietitian can provide guidance and support in navigating food choices and identifying hidden ingredients to avoid with alpha-gal allergy.
Sample Meal Plan for Alpha-Gal Allergy Diet
If you are living with alpha-gal allergy, it may feel overwhelming to plan out your meals and snacks while avoiding potential allergens. Although this AGS meal plan is not customized to specific nutrient needs and is not meant to substitute medical advice, the below sample meal plan for alpha-gal syndrome may help you to visualize a variety of meals and snacks that will work for your needs.
Here is a sample one-day meal plan for someone living with alpha-gal allergy:

Breakfast
Oatmeal with almond milk, topped with fresh berries and chopped nuts
Whole-grain toast with avocado and tomato
Snack
Apple slices with almond butter
Lunch
Grilled chicken salad with mixed greens, cucumber, tomato, and balsamic vinaigrette
Quinoa and vegetable soup
Snack
Carrot sticks with hummus
Dinner
Grilled salmon with roasted vegetables (such as zucchini, bell peppers, and onions)
Sweet potato fries
Dessert
Fresh fruit salad with coconut whipped cream
Note: It is important to work with a registered dietitian to develop a meal plan that meets your nutritional needs and helps you manage your alpha-gal allergy.
Is there a cure for alpha-gal syndrome?
Currently, there is no known cure for alpha-gal allergy. Alpha-gal syndrome is a chronic condition that does not go away on its own. However, the symptoms of alpha-gal allergy can be managed by avoiding foods and products that contain alpha-gal, such as mammalian meat and organs, as well as dairy products made from cow’s, sheep’s, or goat’s milk.
Avoiding tick bites and taking precautions to prevent tick exposure can also help reduce the risk of developing allergic reactions.

In terms of treatment, antihistamines or other allergy medications may be used to manage symptoms if a reaction occurs. In some cases, immunotherapy may be considered as a potential treatment option.
Immunotherapy involves gradually exposing the individual to small amounts of the allergen to desensitize the immune system over time. However, the effectiveness of immunotherapy for alpha-gal allergy is still being studied and is not widely available and should always be done under the supervision of a medical professional.

It is important for individuals with alpha-gal allergy to work closely with their healthcare provider and allergist to develop a personalized management plan that includes avoiding trigger foods and products, carrying emergency medication (such as epinephrine) in case of severe reactions, and seeking medical attention if needed.
Ongoing research is being conducted to better understand alpha-gal allergy and explore potential treatment options in the future.
How can you prevent alpha-gal syndrome?

The best way to prevent AGS is to avoid tick bites, especially those from lone star ticks. To help prevent tick bites, try the following tips:
- Wear protective clothing: When spending time outdoors in areas where ticks are prevalent, wear long-sleeved shirts, long pants, and closed-toe shoes. Tuck your pants into your socks or boots to prevent ticks from crawling up your legs.
- Use tick repellent: Apply an EPA-registered tick repellent to your skin and clothing before heading outdoors. Products containing DEET, picaridin, or permethrin are effective at repelling ticks.
- Check for ticks: After spending time outdoors, check your clothing and body for ticks. Pay close attention to areas such as the scalp, behind the ears, under the arms, and around the waistband.
- Remove ticks promptly: If you find a tick on your body, remove it promptly using fine-tipped tweezers. Grasp the tick as close to the skin’s surface as possible and pull upward with steady, even pressure. Avoid twisting or jerking the tick, as this can cause the mouthparts to break off and remain in the skin. After removing the tick, clean the bite site with soap and water.
- Dry clothes on high heat: Tumble your clothes in a clothes dryer on high for at least one hour before washing them to kill any ticks that may be present.
- Avoid tick habitats: Try to avoid areas where ticks are prevalent, such as dense woods and brushy areas. Stick to cleared paths and avoid sitting on logs, stumps, or the ground in bushy areas.
- Use tick repellent. Using a strong repellent along with the above tips can be your best defense against tick bites.
What are the best tick repellents to use?
The following tick repellents have been found to be effective:
- Ben’s 100 Tick & Insect Repellent: This is a powerful repellent that provides long-lasting protection against ticks and other insects. It contains 98.11% DEET, making it one of the most potent repellents available.
- Natrapel Picaridin Pump: This is a picaridin-based repellent that is just as effective as DEET but has a milder scent. It provides up to 12 hours of protection against ticks and other insects.
- Sawyer Permethrin Insect Repellent: This is a clothing and gear treatment that repels ticks and other insects. It contains permethrin, which is a synthetic insecticide that kills ticks on contact. It provides up to six weeks of protection.
- Yaya Organics Tick Repellent: This is a natural repellent that contains essential oils, such as peppermint, rosemary, and lemongrass. It is safe for use on children and pets and provides up to four hours of protection.
- OFF! Deep Woods Insect Repellent: This is a budget-friendly repellent that contains 25% DEET. It provides up to eight hours of protection against ticks and other insects.
- SITKA Equinox Guard System: This is a hunting clothing system that is treated with permethrin to repel ticks and other insects. It provides long-lasting protection and is designed for use in rugged outdoor environments.
- When choosing a tick repellent, it is important to consider the active ingredients, the duration of protection, and the application method. It is also important to follow the manufacturer’s instructions for use and reapplication.
By taking these precautions, you can reduce your risk of tick bites and the potential development of alpha-gal allergy.
The bottom line on the alpha-gal allergy diet

AGS is a serious and potentially life-threatening allergic reaction to red meat and other products made from mammals. If you think you may have AGS, talk to your healthcare provider and seek immediate emergency care if you are having a severe allergic reaction.
If you are living with AGS, it is important to work with your healthcare provider and a registered dietitian to develop a meal plan that meets your nutritional needs and meets your food preferences, lifestyle, and overall health goals.
